ZHENG, also known as traditional Chinese\r\nmedicine(TCM)syndromeorTCMpattern,isanintegral\r\nand essential part of TCM theory. A TCM ZHENG, in\r\nessence, is a characteristic profile of all clinical\r\nmanifestations that can be identified by a TCM\r\npractitioner. Clinical treatments of a patient rely on the\r\nsuccessfuldifferentiationofaspecificZHENG.Recently,\r\nsomenewtechnologiesandmethodssuchastheSystem\r\nOmics approach were introduced in ZHENG research,\r\nwhichsignificantlyfacilitatethedevelopmentofZHENG\r\ntheory. This review focuses on a brief introduction of\r\nthese new technologies and methods and their\r\napplication in TCM ZHENG differentiation research.\r\nAlso,someofthelatestprogressandapplicationsinthis\r\narea, such as ZHENG measurement, information\r\ncollection, data analysis and mining, ZHENG\r\ndifferentiationbasedTCMtreatment,andmechanismsof\r\nZHENG differentiation based on biological networks\r\nreviewed.
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